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Pro-Test: standing up for science
Pro-Test: Standing Up For Science
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Archives for: May 2006

31/05/06

Permalink 10:03:11 pm, by admin Email , 577 words, 1730 views   English (UK)
Categories: Information

University sends official representative to march with Pro-Test

For the first time, Oxford University is sending an official representative to speak on its behalf at a Pro-Test event: Dr Ken Fleming, Head of the University's Medical Science Division and Member of Council. We are delighted that the University has seized the opportunity to come out and defend the work of its scientists and students in public.

Dr Fleming spoke at our recent public meeting but only in his capacity as Head of Medical Science. He will be appearing in his capacity as a University official on Saturday and we are grateful to him for his participation.

In the meantime, it's become clear what SPEAK will be doing on Saturday. They recently announced that they would be staging a counter-demonstration but were keeping the details secret for 'tactical' reasons - presumably like the location of their forthcoming training camp where they train 'activists' how to violently incapacitate and blind people.

So what are they up to? Well, as an email to their supporters revealed, they have found where the construction workers building the Oxford lab are living - at the Fire Service College at Moreton-in-Marsh - and, after an initial show of force today, they'll be rallying their supporters to harrass and intimidate the builders there.

How sad that instead of making the arguments and trying to win people over in the public domain, SPEAK will again be targeting a group of people whose only interest is to do an honest day's work, in a vicious attempt to yet again delay building on this vital project - and to thereby delay the crucial, life-saving experimentation that is due to take place once the lab is finished. Back in 2004, SPEAK's campaign of intimidation forced Montpellier to pull out of the lab, leading to a 14-month hiatus in building. This was shortly after spiralling security costs - thanks to another SPEAK campaign - caused plans for a similar lab at Cambridge to be shelved. Just last week, a steel company withdrew from the Oxford lab, citing fears of intimidation, and SPEAK are obviously hoping for another success for their campaign of harrassment.

It reflects pretty badly on the anti-vivisectionist movement that they dare not stage a counter-rally in Oxford itself for the very justified fear of being outnumbered, that they would rather bully builders than engage in rational debate and try to win the public over. As the recent Telegraph poll showed, SPEAK and their ilk are losing the argument, haemorraghing public support, and so retreat to trying to frighten people at the margins.

Pro-Test is proud to stand full-square with the construction workers. We signalled our solidarity with the builders earlier this year and urge them to continue refusing to be intimidated off the job. We're campaigning for open, rational discussion of the science and ethics of animal research to build a mass movement in favour of continued vivisection and scientific progress that puts human beings in the centre of our worldview. In doing so, we aim to dispel the climate of fear whipped up by groups like SPEAK, encouraging scientists to defend and promote their work publicly, and showing the 'silent majority' that they don't need to be afraid, that they too can stand up for science.

So, while SPEAK are off bullying builders in an isolated rural town, Pro-Test and its supporters will be rallying on the streets of Oxford, marching for reason, science and progress, with speeches from leading scientists, patients' representatives and university officials. We are Pro-Test... are you?

Permalink 09:33:00 pm, by admin Email , 33 words, 1620 views   English (UK)
Categories: Information

'The shame of our silence'

There is a great op-ed piece on Guardian Unlimited this morning from Prof Lord Robert Winston, the famous genetics expert, encouraging his colleagues to stand up for science at our march on Saturday.

30/05/06

Permalink 03:34:00 pm, by admin Email , 52 words, 1678 views   English (UK)
Categories: Information

March speakers confirmed

Pro-Test will march again this Saturday, 3 June, in Oxford city centre - see here for full details.

Confirmed speakers now include:

Prof Colin Blakemore: Chief Executive of the Medical Research Council

Alan Duncan MP: Shadow Secretary for Trade and Industry

Dr Evan Harris MP: Liberal Democrat Science Spokesman

Niki Shisler: Author and journalist

29/05/06

Permalink 09:37:11 pm, by admin Email , 472 words, 1484 views   English (UK)
Categories: Information

New poll puts support for animal research 'at record high'

A new Telegraph/YouGov poll out today puts support for animal research at a 'record high'. 70% of people surveyed believed that animal testing is acceptable, while 72% felt that there was no alternative. In fact, other surveys have already revealed an even higher level of public support for vivisection, with 77% backing 'any research on animals' in a 1999 New Scientist poll, and 75% in 2002 and 2005 polls for the Coalition for Medical Progress, with 90% backing the research so long as suffering was minimised (which it always is). See today's poll data here and an op-ed piece by Prof Colin Blakemore describing the shift in opinion over the last 20 years here.

What the latest poll actually seems to show is outright opposition to animal testing at an all time low. Only 18% think testing drugs on animals before humans is unacceptable under any circumstances, with 11% saying they don't know; only 19% believe alternatives are available and 9% didn't know.

Today's survey mixes the questions on animal research with questions on animal rights extremism, and it's noteworthy that more people are firmly opposed to the extremism than are strongly in favour of animal research. This is to be expected, especially given that people continue to be targeted, but it shows that there is still a sizeable part of the population who are yet to be won over to the pro-testing side on the basis of the scientific and ethical arguments. As the Telegraph's leader notes, the results are partly due to Pro-Test's organisation of a public, pro-science movement, but also partly due to a backlash against extremism.

A huge, overwhelming majority back animal research. Scientists should take heart from today's figures, which are, as Blakemore says, a sign of the changing climate around the animal testing issue. As the Telegraph says, it certainly undermines anti-vivisectionists' claims to enjoy majority support. But neither scientists, nor groups like Pro-Test, can afford to be complacent. Around 10% of the public still don't know where they stand on the issue, while nearly 20% erroneously believe there are viable alternatives to animal research available now, and nearly 20% are opposed to testing medical treatments (not research in general - specifically, medical treatments) on animals before humans. Even if the tide has turned against animal rights extremism, we are still a long way from a climate where the science of animal research is properly understood and scientists can command the respect they deserve for the work they do, and the freedom they need to do it.

Also in the press: Kate Hoey MP alleges that the Labour party's acceptance of funding from animal rights groups 'gave them credibility'; The Glasgow Sunday Herald notes a small rush among GSK shareholders to remove their details from the public arena, and argues, as Pro-Test has been arguing, for business to rely on making the positive case for animal testing, rather than relying on secrecy.

Permalink 04:21:59 pm, by admin Email , 14 words, 1648 views   English (UK)
Categories: News

Next March!

Pro-Test's next march will take place this Saturday, 3 June at 11.45am in central Oxford.

28/05/06

Permalink 11:03:32 pm, by admin Email , 49 words, 1658 views   English (UK)
Categories: Information

Lady Margaret Hall and Pembroke College JCRs are Pro-Test!

Another JCR has stood up for science by passing Pro-Test's motion in support of Oxford's new biomedical research facility: Pembroke JCR joins the JCRs of New, St John's, Wadham and Corpus Christi Colleges, and the MCR of Merton College on the roll-call of our 'Oxford Declaration'.

Well done, Pembroke!

Permalink 06:52:33 pm, by admin Email , 169 words, 1721 views   English (UK)
Categories: Information

Some recent press

There was an interesting op-ed piece in the Observer last Sunday, arguing that there is no middle way on drug testing: given the current level of scientific knowledge (the lack of genuine alternatives to animal-based research) anti-vivisectionists need to make the argument for testing on humans. On this, we completely agree. Anti-vivisectionists are generally extremely disingenuous, pretending that the alternatives already exist, and rarely admitting what a ban on animal research would mean for humans. Pro-Test seeks to draw them out on this point. At a recent debate at Sheffield University between Pro-Test member Kristina Cook and Jarrod Bailey from Europeans for Medical 'Progress' (full write-up coming soon from an audience member), Kristina pointed out Dr Bailey would prefer to test drugs on members of the audience rather than animals. Bailey responded: "Well, yes I guess I would rather test on members of this audience but, um..."

See also: Prof John Stein of Pro-Test, in the Guardian, and a profile of Pro-Test in the New York publication, Seed Magazine

25/05/06

Permalink 10:00:00 pm, by admin Email , 78 words, 1633 views   English (UK)
Categories: Information

Merton College MCR is Pro-Test!

Merton College's Middle Common Room (graduate students) has become the latest student body in Oxford to pass Pro-Test's motion in support of the Oxford lab, continued vivisection and scientific progress. There was a fruitful debate of all the issues, and the final vote was carried overwhelmingly, with only 2 'nays' and 2 abstentions. Well done, Merton!

Merton's MCR joins New, Wadham, Corpus Christi and St John's College Junior Common Rooms (undergraduates) on the 'Oxford Declaration' in support of the lab.

22/05/06

Permalink 04:21:19 pm, by admin Email , 11 words, 1472 views   English (UK)
Categories: News

Public Meeting Success!

Our public meeting was a great success. See a write-up here.

21/05/06

Permalink 04:19:21 pm, by admin Email , 21 words, 1565 views   English (UK)
Categories: News

First Public Meeting

Pro-Test's first Public Meeting is being held tomorrow at the Oxford Town Hall. See the Get Involved page for full details!

16/05/06

Permalink 04:18:44 pm, by admin Email , 41 words, 1732 views   English (UK)
Categories: News

GlaxoSmithKline's AGM

Pro-Test members Laurie Pycroft and Chris Bickerton will be attending GlaxoSmithKline's AGM today to express our support for the company's work and the shareholders being targeted by animal rights extremists. Pro-Test recently bought 10 shares in GSK as a gesture of solidarity.

13/05/06

Permalink 04:16:29 pm, by admin Email , 24 words, 1635 views   English (UK)
Categories: News

Public Meeting

Pro-Test is holding a public meeting at the Oxford Town Hall on the evening of Monday, 22 May. Full details on the Get Involved page.

09/05/06

Permalink 04:15:58 pm, by admin Email , 25 words, 1525 views   English (UK)
Categories: News

Next Demonstration

We can now confirm that the next demonstration will be held in Oxford at 11.45am on Saturday 3 June. Full details on the Get Involved page.

01/05/06

Permalink 11:59:00 pm, by admin Email , 464 words, 5288 views   English (UK)
Categories: Information

"New” breast-cancer drug progresses to human trials

Author: Dr Imre Hunyor, guest writer on standupforscience

One purpose of this blog is to highlight the ever-increasing number of scientific findings that illustrate the benefits of animal testing for human health. Not all of us have time to digest the intricacies of peer-reviewed scientific journals and are forced to rely on the popular press to tell us about the latest medical research. Often, the reliance on animal testing is assumed and not reported.

This week, human trials have begun using a previously known anticancer drug, carboplatin, which could transform anticancer treatment for women who develop breast cancer as a result of a common genetic mutation (Reference 1 & 2). Carboplatin has been around for a long time and is often used in the treatment of lung and ovarian cancers, but has not been tested in the subset of breast cancer caused by mutations in the genes BRCA1 and 2 (present in about 5% of breast cancer patients). Carriers of a mutation in BRCA1 are thought to have a 50 to 85 percent lifetime risk of breast cancer and a 20 to 40 percent lifetime risk of ovarian cancer. Women with a mutation in BRCA2 appear to have a similar risk of breast cancer and a 10 to 20 percent risk of ovarian cancer (3).

Cancers are well known to arise from DNA mutations, so mimicking this in animals makes for a viable and accurate model. The key issue I would like to highlight here is that researchers had been able to create the genetic mutation in a breed of mice (4), and thus test carboplatin in this animal model of human disease. The rodent model demonstrated that cells with a mutation in the BRCA gene are more sensitive to carboplatin compared with normal cells.

Following confirmation in other laboratory experiments and pre-clinical trials, human clinical trials of carboplatin in patients with breast cancer and the BRCA1/2 mutation are now underway. Previous animal studies and years of use for the treatment of other cancers in humans have the allowed rapid progression to human clinical trials.

Animal testing is not a guarantee of a successful outcome in humans – but our understanding of breast cancer and the discovery that carboplatin could be effective for a subgroup of patients with the disease was possible through investigations involving animals.

(1) An excellent website describing the current trial and its scientific rationale (far more detailed than in this blog) can be found at www.geneticbreastcancertrial.usilu.net/Home.html
(2) Lung cancer drug may fight breast tumour in women , The Times, May 1, 2006.
(3) Haber, D. Prophylactic oophorectomy to reduce the risk of ovarian and breast cancer in carriers of BRCA mutations. N Engl J Med May 23; 346 (21) 1660-2 (2002)
(4) Fedier, A., et al. The effect of loss of brca1 on the sensitivity to anticancer agents in p53-deficient cells. Int J Oncol 22, 1169-73 (2003).

Originally Posted by Kristina Cook.

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